months after decision
base-case estimate: mortality risk (if seroconverted) increased by 4.12% HIV, 3.42% HCV per year
worst-case estimate: mortality risk (if seroconverted) equivalent to immediate (100% chance) death
When a patient with end stage renal disease (ESRD) on the waitlist for a kidney is offered an Infectious Risk Donor (IRD) kidney, they need to decide whether they will accept the IRD kidney and the associated infectious risk, or if they will decline it and continue to wait for the next available infectious-risk free kidney. Infectious Risk Donors (IRD) are individuals who had high-risk behaviors that puts them at increased risk of transmitting HIV or HCV to recipients of their organs. This calculator is based on data reported to OPTN/SRTR from 2002-2010 and predicts the chance of survival for when the patient chooses one alternative over the other. Some centers use Nucleic Acid Testing (NAT) while others use Enzyme-linked Immunosorbent Assay (ELISA) serology testing on IRD kidneys; in general, the risk of seroconversion with ELISA tested kidneys is 10X greater than NAT.
Based on research done by Chow EK, Massie AB, Muzaale AD, Singer AL, Kucirka LM, Lehmann H, Montgomery RA, Segev DL
Disclaimer: This software is provided 'as is' and comes with ABSOLUTELY NO WARRANTY. In no event shall the authors or contributors be liable for any direct, indirect, incidental, special, exemplary, or consequential damages however caused and on any theory of liability, whether in contract, strict liability, or tort arising in any way out of the use of this software, even if advised of the possibility of such damage.
Learn more about the Kidney Transplant Program at Johns Hopkins.