Transplant Models

The Epidemiology Research Group for Organ Transplantation is a research group focused on organ transplantation at the Johns Hopkins School of Medicine. Below are some of the decision models we have developed.

Infectious Risk Donors

When a patient with end stage renal disease (ESRD) on the waitlist for a kidney is offered an Infectious Risk Donor (IRD) kidney, they need to decide whether they will accept the IRD kidney and the associated infectious risk, or if they will decline it and continue to wait for the next available infectious-risk free kidney ...

Chow, E. K. H., Massie, A. B., Muzaale, A. D., Singer, A. L., Kucirka, L. M., Montgomery, R. A., ... & Segev, D. L. (2013). Identifying appropriate recipients for CDC infectious risk donor kidneys. American Journal of Transplantation, 13(5), 1227-1234.

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Transplant Candidacy for Patients 65+

This prediction model is intended for adults with ESRD on dialysis aged 65 and above; it provides the predicted probability of 3-year survival after kidney transplantation (KT). Patients with predicted 3-year post-KT survival in the top quintile are deemed "excellent" candidates ...

Grams, M. E., Kucirka, L. M., Hanrahan, C. F., Montgomery, R. A., Massie, A. B., & Segev, D. L. (2012). Candidacy for kidney transplantation of older adults. Journal of the American Geriatrics Society, 60(1), 1-7.

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Pediatric Transplant: Living or deceased donor first?

Most pediatric kidney transplant recipients live long enough to require retransplantation. The most beneficial timing for living donor transplantation in candidates with one living donor is not clear...

Van Arendonk, K. J., Chow, E. K., James, N. T., Orandi, B. J., Ellison, T. A., Smith, J. M., Colombani, P. M., & Segev, D. L. (2012). Choosing the Order of Deceased Donor and Living Donor Kidney Transplantation in Pediatric Recipients: A Markov Decision Process Model. Am J Transplant, XX(X), XXX.

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